BIB seeks daily investment results, before fees and expenses, that correspond to two times (2x) the daily performance of the Nasdaq Biotechnology® Index.
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Performance
30 Day Daily Return
Chart is updated nightly to reflect the more recent of the previous day's market closing price or the closing price on the day the fund was last traded.
Total Return
Month-End Total Returns as of 3/31/2026
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| Fund | 1m | 3m | 6m | YTD | 1Y | 3Y | 5Y | 10Y | Since Inception | Inception Date |
|---|---|---|---|---|---|---|---|---|---|---|
| BIB Market Price | -7.52% | 2.18% | 37.06% | 2.18% | 70.63% | 15.62% | 0.04% | 7.44% | 16.31% | 04/07/2010 |
| BIB NAV | -7.55% | 2.21% | 37.13% | 2.21% | 70.94% | 15.59% | 0.06% | 7.43% | 16.31% | 04/07/2010 |
The performance quoted represents past performance and does not guarantee future results. Investment return and principal value of an investment will fluctuate so that an investor's shares, when sold or redeemed, may be worth more or less than the original cost. Shares are bought and sold at market price (not NAV) and are not individually redeemed from the fund. Market price returns are based upon the midpoint of the bid/ask spread at 4:00 p.m. ET (when NAV is normally determined for most funds) and do not represent the returns you would receive if you traded shares at other times. Your brokerage commissions will reduce returns. Current performance may be lower or higher than the performance quoted. For standardized returns and performance data current to the most recent month end, see above.
About the Fund
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $75,007,790
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/28/2026- NAV
- NAV Change
- Market Price $80.64
- Market Price Change $-1.45
- Trading Volume (M) 4,415
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Snapshot
- Ticker BIB
- Intraday Ticker BIB.IV
- CUSIP 74347R214
- Inception Date 4/7/10
- Net Assets $75,007,790
- Gross Expense Ratio 1.19%
- Net Expense Ratio 0.95%
- NAV Calculation Time
- Distributions Quarterly
- Options Available Yes
Price
as of 4/28/2026- NAV
- NAV Change
- Market Price $80.64
- Market Price Change $-1.45
- Trading Volume (M) 4,415
- 30-Day Median Bid Ask Spread 0.24%
- View Premium / Discount
Expenses with Contractual Waiver through September 30, 2025. Without the fee waiver performance would likely be lower.
Exposures
Index as of 3/31/2026
Holdings
as of 4/28/2026
| Exposure Weight | Ticker | Description | Exposure Value (Notional + GL) |
Market Value | Shares/Contracts | SEDOL Number |
|---|---|---|---|---|---|---|
| 4.89% | AMGN | AMGEN INC | -- | $3,664,299.87 | 10,791 | 2023607 |
| 4.85% | GILD | GILEAD SCIENCES INC | -- | $3,634,920.46 | 28,121 | 2369174 |
| 4.83% | VRTX | VERTEX PHARMACEUTICALS INC | -- | $3,625,650.06 | 8,429 | 2931034 |
| 4.12% | REGN | REGENERON PHARMACEUTICALS | -- | $3,093,191.79 | 4,227 | 2730190 |
| 2.17% | ALNY | ALNYLAM PHARMACEUTICALS INC | -- | $1,630,185.56 | 5,396 | B00FWN1 |
| 1.58% | INSM | INSMED INC | -- | $1,183,828.62 | 8,773 | 2614487 |
| 1.56% | RVMD | REVOLUTION MEDICINES INC | -- | $1,168,053.95 | 8,065 | BL71K91 |
| 1.46% | BIIB | BIOGEN INC | -- | $1,094,961.98 | 5,971 | 2455965 |
| 1.35% | UTHR | UNITED THERAPEUTICS CORP | -- | $1,014,723.13 | 1,783 | 2430412 |
| 1.19% | ARGX | ARGENX SE - ADR | -- | $895,159.65 | 1,155 | BDVLM39 |
| 1.15% | RPRX | ROYALTY PHARMA PLC- CL A | -- | $863,779.44 | 17,436 | BMVP7Y0 |
| 1.08% | ROIV | ROIVANT SCIENCES LTD | -- | $809,051.18 | 29,134 | BMW4NZ9 |
| 1.06% | INCY | INCYTE CORP | -- | $791,889.48 | 8,102 | 2471950 |
| 1.05% | ILMN | ILLUMINA INC | -- | $789,950.08 | 6,224 | 2613990 |
| 1.01% | MRNA | MODERNA INC | -- | $757,681.22 | 16,073 | BGSXTS3 |
| 0.93% | VTRS | VIATRIS INC | -- | $694,539.30 | 46,865 | BMWS3X9 |
| 0.89% | SMMT | SUMMIT THERAPEUTICS INC | -- | $670,965.60 | 31,560 | BMTVQS7 |
| 0.74% | -- | ASCENDIS PHARMA A/S | -- | $556,310.40 | 2,505 | -- |
| 0.73% | BBIO | BRIDGEBIO PHARMA INC | -- | $550,081.61 | 7,891 | BK1KWG8 |
| 0.70% | NBIX | NEUROCRINE BIOSCIENCES INC | -- | $523,498.32 | 4,086 | 2623911 |
| 0.68% | JAZZ | JAZZ PHARMACEUTICALS PLC | -- | $510,969.90 | 2,505 | B4Q5ZN4 |
| 0.64% | IONS | IONIS PHARMACEUTICALS INC | -- | $482,720.50 | 6,725 | BDJ0LS6 |
| 0.64% | MDGL | MADRIGAL PHARMACEUTICALS INC | -- | $482,588.46 | 934 | BD59BS7 |
| 0.63% | EXEL | EXELIXIS INC | -- | $474,955.03 | 10,571 | 2576941 |
| 0.63% | BNTX | BIONTECH SE-ADR | -- | $473,252.22 | 4,637 | BK6H543 |
| 0.63% | MEDP | MEDPACE HOLDINGS INC | -- | $473,145.75 | 1,155 | BDCBC61 |
| 0.61% | SNY | SANOFI-ADR | -- | $457,662.00 | 9,960 | 2964557 |
| 0.59% | GH | GUARDANT HEALTH INC | -- | $443,451.33 | 5,337 | BFXC911 |
| 0.56% | BMRN | BIOMARIN PHARMACEUTICAL INC | -- | $417,232.40 | 7,828 | 2437071 |
| 0.53% | ARWR | ARROWHEAD PHARMACEUTICALS IN | -- | $399,881.26 | 5,702 | BYQBFJ8 |
| 0.52% | ONC | BEONE MEDICINES LTD-ADR | -- | $387,906.16 | 1,301 | BYYWPW6 |
| 0.51% | AXSM | AXSOME THERAPEUTICS INC | -- | $385,170.00 | 2,082 | BYZR4X4 |
| 0.49% | PRAX | PRAXIS PRECISION MEDICINES I | -- | $365,057.28 | 1,134 | BQ721R4 |
| 0.48% | TEM | TEMPUS AI INC-CL A | -- | $361,277.00 | 7,070 | BSLSJJ0 |
| 0.46% | PCVX | VAXCYTE INC | -- | $343,981.61 | 5,857 | BKPVGH6 |
| 0.43% | KRYS | KRYSTAL BIOTECH INC | -- | $320,969.84 | 1,192 | BD6JX35 |
| 0.41% | HALO | HALOZYME THERAPEUTICS INC | -- | $306,783.44 | 4,804 | 2975098 |
| 0.41% | CYTK | CYTOKINETICS INC | -- | $304,299.66 | 5,014 | BBBSBJ5 |
| 0.41% | NUVL | NUVALENT INC-A | -- | $303,781.20 | 2,980 | BMVBZD3 |
| 0.39% | IBRX | IMMUNITYBIO INC | -- | $291,269.04 | 41,849 | BNSP0B8 |
| 0.37% | KYMR | KYMERA THERAPEUTICS INC | -- | $278,465.85 | 3,321 | BMPRZV5 |
| 0.37% | ABVX | ABIVAX SA-ADR | -- | $274,565.13 | 2,499 | BLC89B2 |
| 0.35% | PTGX | PROTAGONIST THERAPEUTICS INC | -- | $262,943.58 | 2,598 | BDCBCD8 |
| 0.32% | COGT | COGENT BIOSCIENCES INC | -- | $240,134.72 | 6,608 | BLR6XK8 |
| 0.32% | PTCT | PTC THERAPEUTICS INC | -- | $236,635.68 | 3,368 | B17VCN9 |
| 0.31% | RYTM | RHYTHM PHARMACEUTICALS INC | -- | $234,020.40 | 2,780 | BF2YWG4 |
| 0.31% | ALKS | ALKERMES PLC | -- | $231,605.76 | 6,784 | B3P6D26 |
| 0.31% | MIRM | MIRUM PHARMACEUTICALS INC | -- | $230,864.00 | 2,456 | BJDX8Y8 |
| 0.31% | TERN | TERNS PHARMACEUTICALS INC | -- | $229,177.26 | 4,329 | BMDJ0C9 |
| 0.30% | CGON | CG ONCOLOGY INC | -- | $225,295.35 | 3,437 | BRBCSP4 |
| 0.30% | IMVT | IMMUNOVANT INC | -- | $223,666.13 | 8,287 | BJRFSB7 |
| 0.29% | SYRE | SPYRE THERAPEUTICS INC | -- | $219,341.48 | 3,196 | BQBBDY8 |
| 0.28% | APLS | APELLIS PHARMACEUTICALS INC | -- | $213,270.97 | 5,203 | BYTQ6X1 |
| 0.28% | CAI | CARIS LIFE SCIENCES INC | -- | $211,801.84 | 11,486 | BT18HP9 |
| 0.27% | CRSP | CRISPR THERAPEUTICS AG | -- | $203,398.42 | 3,907 | BDHF4K6 |
| 0.26% | SRRK | SCHOLAR ROCK HOLDING CORP | -- | $194,116.42 | 4,154 | BFZQ0L8 |
| 0.26% | CNTA | CENTESSA PHARMACEUTICALS-ADR | -- | $192,130.74 | 4,869 | BLB0YQ9 |
| 0.25% | APGE | APOGEE THERAPEUTICS INC | -- | $190,460.47 | 2,231 | BM9HHL5 |
| 0.25% | LGND | LIGAND PHARMACEUTICALS | -- | $188,179.20 | 810 | 2501578 |
| 0.25% | XENE | XENON PHARMACEUTICALS INC | -- | $184,638.58 | 3,386 | BRJ3GY4 |
| 0.23% | INDV | INDIVIOR PHARMACEUTICALS INC | -- | $175,179.84 | 5,088 | BTZRLN8 |
| 0.22% | AMRX | AMNEAL PHARMACEUTICALS INC | -- | $163,084.41 | 12,806 | BFNF1D6 |
| 0.22% | CRNX | CRINETICS PHARMACEUTICALS IN | -- | $162,595.30 | 4,262 | BDD19F8 |
| 0.21% | ACAD | ACADIA PHARMACEUTICALS INC | -- | $157,261.79 | 6,937 | 2713317 |
| 0.20% | TVTX | TRAVERE THERAPEUTICS INC | -- | $153,541.95 | 3,755 | BLFGJD5 |
| 0.20% | TWST | TWIST BIOSCIENCE CORP | -- | $147,638.40 | 2,496 | BGKG6G7 |
| 0.19% | ORKA | ORUKA THERAPEUTICS INC | -- | $145,760.30 | 1,970 | BKVF0J2 |
| 0.18% | GPCR | STRUCTURE THERAPEUTICS INC | -- | $138,215.88 | 3,173 | BQS9486 |
| 0.18% | TNGX | TANGO THERAPEUTICS INC | -- | $137,817.48 | 5,482 | BP2P6L0 |
| 0.18% | EWTX | EDGEWISE THERAPEUTICS INC | -- | $135,302.34 | 4,366 | BKY5JZ8 |
| 0.18% | -- | NEWAMSTERDAM PHARMA CO NV | -- | $134,352.16 | 4,678 | BP8JSP4 |
| 0.17% | DNLI | DENALI THERAPEUTICS INC | -- | $129,467.24 | 6,454 | BD2B4V0 |
| 0.17% | BEAM | BEAM THERAPEUTICS INC | -- | $126,732.32 | 4,147 | BK6L288 |
| 0.17% | ERAS | ERASCA INC | -- | $124,769.70 | 12,603 | BNLYBF3 |
| 0.16% | ALMS | ALUMIS INC | -- | $123,606.92 | 5,146 | BPLQG36 |
| 0.16% | DYN | DYNE THERAPEUTICS INC | -- | $121,672.00 | 6,700 | BN15WD1 |
| 0.16% | ARQT | ARCUTIS BIOTHERAPEUTICS INC | -- | $117,474.76 | 5,044 | BKX9VD3 |
| 0.15% | SUPN | SUPERNUS PHARMACEUTICALS INC | -- | $113,642.46 | 2,334 | B72ZBG4 |
| 0.15% | KOD | KODIAK SCIENCES INC | -- | $112,848.12 | 2,484 | BFXC933 |
| 0.14% | VCYT | VERACYTE INC | -- | $108,212.91 | 3,237 | BFTWZY0 |
| 0.14% | VERA | VERA THERAPEUTICS INC | -- | $107,767.44 | 2,904 | BL55460 |
| 0.14% | TARS | TARSUS PHARMACEUTICALS INC | -- | $107,539.88 | 1,732 | BMH5RL1 |
| 0.14% | ADMA | ADMA BIOLOGICS INC | -- | $105,675.50 | 9,695 | B9NSBM2 |
| 0.14% | IRON | DISC MEDICINE INC | -- | $104,522.04 | 1,554 | BMGJZJ8 |
| 0.14% | ELVN | ENLIVEN THERAPEUTICS INC | -- | $103,882.66 | 2,417 | BMFD115 |
| 0.14% | IDYA | IDEAYA BIOSCIENCES INC | -- | $103,818.00 | 3,575 | BK0VHF6 |
| 0.14% | TXG | 10X GENOMICS INC-CLASS A | -- | $102,319.56 | 4,788 | BKS3RS7 |
| 0.13% | KNSA | KINIKSA PHARMACEUTICALS INTE | -- | $100,699.50 | 1,870 | BRXB0C0 |
| 0.13% | RARE | ULTRAGENYX PHARMACEUTICAL IN | -- | $96,476.49 | 3,933 | BJ62Z18 |
| 0.13% | RLAY | RELAY THERAPEUTICS INC | -- | $94,793.25 | 7,275 | BN2R582 |
| 0.12% | BCRX | BIOCRYST PHARMACEUTICALS INC | -- | $90,460.60 | 10,210 | 2100362 |
| 0.12% | SRPT | SAREPTA THERAPEUTICS INC | -- | $89,884.62 | 4,266 | B8DPDT7 |
| 0.12% | ADPT | ADAPTIVE BIOTECHNOLOGIES | -- | $87,988.68 | 6,267 | BJ5FZ74 |
| 0.12% | AUPH | AURINIA PHARMACEUTICALS INC | -- | $86,808.48 | 5,412 | BFWLC09 |
| 0.12% | DFTX | DEFINIUM THERAPEUTICS INC | -- | $86,313.66 | 4,058 | BV2DHY6 |
| 0.11% | ZYME | ZYMEWORKS INC | -- | $85,161.12 | 3,048 | BPCQZY9 |
| 0.11% | MLYS | MINERALYS THERAPEUTICS INC | -- | $83,417.58 | 3,222 | BP9N0G0 |
| 0.11% | GRAL | GRAIL INC | -- | $82,684.80 | 1,584 | BSLSSX7 |
| 0.11% | OCUL | OCULAR THERAPEUTIX INC | -- | $82,584.52 | 8,861 | BNZB1X8 |
| 0.11% | LEGN | LEGEND BIOTECH CORP-ADR | -- | $80,928.60 | 3,435 | BMX9K07 |
| 0.10% | STOK | STOKE THERAPEUTICS INC | -- | $77,458.92 | 2,324 | BJQ05Z6 |
| 0.10% | INBX | INHIBRX BIOSCIENCES INC | -- | $77,223.02 | 591 | BNSP8K3 |
| 0.10% | TYRA | TYRA BIOSCIENCES INC | -- | $76,150.32 | 2,172 | BMVNDH9 |
| 0.10% | SNDX | SYNDAX PHARMACEUTICALS INC | -- | $75,806.01 | 3,591 | BN7Q7R7 |
| 0.10% | ANAB | ANAPTYSBIO INC | -- | $74,638.19 | 1,129 | BDRW1L7 |
| 0.10% | VCEL | VERICEL CORP | -- | $73,688.55 | 2,067 | BSBMN89 |
| 0.10% | PHVS | PHARVARIS NV | -- | $73,597.76 | 2,608 | BMZ2X38 |
| 0.10% | HRMY | HARMONY BIOSCIENCES HOLDINGS | -- | $73,381.80 | 2,355 | BKSGZN7 |
| 0.10% | AMLX | AMYLYX PHARMACEUTICALS INC | -- | $72,938.32 | 4,472 | BPCK358 |
| 0.10% | RXRX | RECURSION PHARMACEUTICALS-A | -- | $72,448.86 | 21,246 | BM9FJ13 |
| 0.10% | TRVI | TREVI THERAPEUTICS INC | -- | $72,217.12 | 5,218 | BJH9ZN0 |
| 0.10% | SION | SIONNA THERAPEUTICS INC | -- | $71,974.62 | 1,818 | BQKXDX4 |
| 0.10% | ANIP | ANI PHARMACEUTICALS INC | -- | $71,670.50 | 913 | BCDWBX6 |
| 0.10% | NRIX | NURIX THERAPEUTICS INC | -- | $71,496.88 | 4,186 | BMVLGP2 |
| 0.10% | INVA | INNOVIVA INC | -- | $71,401.66 | 3,014 | BDDXF67 |
| 0.09% | TSHA | TAYSHA GENE THERAPIES INC | -- | $70,232.40 | 11,148 | BNC1BX1 |
| 0.09% | GMAB | GENMAB A/S -SP ADR | -- | $70,216.59 | 2,621 | BBC9WC7 |
| 0.09% | VIR | VIR BIOTECHNOLOGY INC | -- | $65,750.88 | 6,396 | BK4PZ38 |
| 0.09% | RAPP | RAPPORT THERAPEUTICS INC | -- | $65,489.34 | 1,941 | BR3T9B6 |
| 0.09% | ATAI | ATAIBECKLEY INC | -- | $64,010.39 | 14,783 | BWJDYK1 |
| 0.08% | NTLA | INTELLIA THERAPEUTICS INC | -- | $63,465.60 | 4,808 | BYZM6C2 |
| 0.08% | HROW | HARROW INC | -- | $61,165.28 | 1,511 | BHNDW86 |
| 0.08% | ARDX | ARDELYX INC | -- | $59,586.57 | 9,981 | BN89V40 |
| 0.08% | AGIO | AGIOS PHARMACEUTICALS INC | -- | $59,123.20 | 2,384 | BCBVTX1 |
| 0.08% | GLUE | MONTE ROSA THERAPEUTICS INC | -- | $59,026.05 | 3,105 | BP7KZP7 |
| 0.08% | PGEN | PRECIGEN INC | -- | $57,904.08 | 14,404 | BKM5C84 |
| 0.08% | WVE | WAVE LIFE SCIENCES LTD | -- | $57,625.76 | 7,663 | BYZG9R0 |
| 0.08% | IOVA | IOVANCE BIOTHERAPEUTICS INC | -- | $56,675.84 | 16,768 | BF0DMK7 |
| 0.08% | BCAX | BICARA THERAPEUTICS INC | -- | $56,531.68 | 2,579 | BQB42F1 |
| 0.07% | NVCR | NOVOCURE LTD | -- | $56,139.84 | 4,632 | BYSS4X4 |
| 0.07% | MBX | MBX BIOSCIENCES INC | -- | $53,027.04 | 1,826 | BQXJKH2 |
| 0.07% | CRVS | CORVUS PHARMACEUTICALS INC | -- | $52,514.44 | 3,362 | BYP80F1 |
| 0.07% | NVAX | NOVAVAX INC | -- | $52,501.68 | 6,629 | BJDQXG4 |
| 0.07% | IMCR | IMMUNOCORE HOLDINGS PLC-ADR | -- | $51,361.36 | 1,784 | BLCD809 |
| 0.07% | ABCL | ABCELLERA BIOLOGICS INC | -- | $51,334.40 | 12,340 | BL53SR3 |
| 0.07% | MAZE | MAZE THERAPEUTICS INC | -- | $50,810.10 | 1,958 | BSRK699 |
| 0.07% | AVBP | ARRIVENT BIOPHARMA INC | -- | $50,527.28 | 1,682 | BMGTLY5 |
| 0.07% | GHRS | GH RESEARCH PLC | -- | $50,141.10 | 2,526 | BP6C0S2 |
| 0.06% | OLMA | OLEMA PHARMACEUTICALS INC | -- | $47,577.99 | 3,261 | BMZ4LN0 |
| 0.06% | ALVO | ALVOTECH SA | -- | $47,326.40 | 13,445 | BPNTJ34 |
| 0.06% | URGN | UROGEN PHARMA LTD | -- | $45,924.48 | 1,904 | BZ7PJQ1 |
| 0.06% | QURE | UNIQURE NV | -- | $45,774.80 | 2,536 | BJFSR88 |
| 0.06% | PAHC | PHIBRO ANIMAL HEALTH CORP-A | -- | $45,549.31 | 839 | BL95N25 |
| 0.06% | EYPT | EYEPOINT INC | -- | $45,380.43 | 3,369 | BMGS7L1 |
| 0.06% | SEPN | SEPTERNA INC | -- | $44,232.09 | 1,821 | BQNKXX2 |
| 0.06% | COLL | COLLEGIUM PHARMACEUTICAL INC | -- | $42,390.52 | 1,292 | BX7RSN3 |
| 0.06% | OMER | OMEROS CORP | -- | $42,308.28 | 2,884 | B4NB858 |
| 0.06% | PCRX | PACIRA BIOSCIENCES INC | -- | $41,799.45 | 1,645 | B3X26D8 |
| 0.06% | SVRA | SAVARA INC | -- | $41,590.70 | 8,285 | BYXGN81 |
| 0.05% | XERS | XERIS BIOPHARMA HOLDINGS INC | -- | $41,131.86 | 6,754 | BLR7H87 |
| 0.05% | FTRE | FORTREA HOLDINGS INC | -- | $40,941.80 | 3,805 | BRXYZ57 |
| 0.05% | AMPH | AMPHASTAR PHARMACEUTICALS IN | -- | $40,279.72 | 1,846 | BNFWZS4 |
| 0.05% | GRFS | GRIFOLS SA-ADR | -- | $40,051.41 | 4,963 | B8K7T65 |
| 0.05% | ZBIO | ZENAS BIOPHARMA INC | -- | $39,964.19 | 2,219 | BQB42H3 |
| 0.05% | KALV | KALVISTA PHARMACEUTICALS INC | -- | $39,595.92 | 2,058 | BD06CS0 |
| 0.05% | ORIC | ORIC PHARMACEUTICALS INC | -- | $39,429.90 | 4,086 | BKVDFF7 |
| 0.05% | GERN | GERON CORP | -- | $39,237.35 | 25,985 | 2370381 |
| 0.05% | SANA | SANA BIOTECHNOLOGY INC | -- | $36,324.05 | 10,843 | BMFJJ97 |
| 0.05% | PHAT | PHATHOM PHARMACEUTICALS INC | -- | $36,323.98 | 3,206 | BJLKVS6 |
| 0.05% | XNCR | XENCOR INC | -- | $36,292.05 | 2,987 | BGCYWN8 |
| 0.05% | JANX | JANUX THERAPEUTICS INC | -- | $35,916.50 | 2,477 | BMFX8Y7 |
| 0.05% | ANNX | ANNEXON INC | -- | $35,346.00 | 5,891 | BMVV9R5 |
| 0.05% | MNKD | MANNKIND CORP | -- | $34,992.18 | 12,542 | BF081J4 |
| 0.05% | TBPH | THERAVANCE BIOPHARMA INC | -- | $34,592.64 | 2,064 | BMNDK09 |
| 0.04% | ABUS | ARBUTUS BIOPHARMA CORP | -- | $32,486.20 | 7,828 | BZ0QMB7 |
| 0.04% | CMPS | COMPASS PATHWAYS PLC | -- | $32,409.60 | 3,840 | BMC3HS7 |
| 0.04% | MESO | MESOBLAST LTD- SPON ADR | -- | $32,403.38 | 2,129 | BQS7491 |
| 0.04% | SPRY | ARS PHARMACEUTICALS INC | -- | $31,958.50 | 4,025 | BMCR7V2 |
| 0.04% | KURA | KURA ONCOLOGY INC | -- | $31,275.86 | 3,542 | BYZD465 |
| 0.04% | ZLAB | ZAI LAB LTD-ADR | -- | $30,885.30 | 1,395 | BD9GVY0 |
| 0.04% | CGEM | CULLINAN THERAPEUTICS INC | -- | $30,820.86 | 2,406 | BM90J52 |
| 0.04% | BIOA | BIOAGE LABS INC | -- | $30,816.48 | 1,767 | BT9K6D8 |
| 0.04% | CSTL | CASTLE BIOSCIENCES INC | -- | $29,874.90 | 1,210 | BKLCWZ3 |
| 0.04% | ABSI | ABSCI CORP | -- | $29,748.06 | 6,121 | BN94K69 |
| 0.04% | MGTX | MEIRAGTX HOLDINGS PLC | -- | $29,746.08 | 3,276 | BFYQFJ2 |
| 0.04% | DSGN | DESIGN THERAPEUTICS INC | -- | $29,680.77 | 2,317 | BMFK3H6 |
| 0.04% | CTMX | CYTOMX THERAPEUTICS INC | -- | $28,411.52 | 6,896 | BYWVTY5 |
| 0.04% | IRWD | IRONWOOD PHARMACEUTICALS INC | -- | $27,816.60 | 6,623 | B3MZ6K5 |
| 0.04% | PRME | PRIME MEDICINE INC | -- | $27,110.43 | 7,347 | BPBJFM7 |
| 0.04% | ARVN | ARVINAS INC | -- | $26,612.88 | 2,604 | BDZ30Q0 |
| 0.04% | ETON | ETON PHARMACEUTICALS INC | -- | $26,358.56 | 1,091 | BGL0JK3 |
| 0.03% | PRTA | PROTHENA CORP PLC | -- | $25,195.39 | 2,189 | B91XRN2 |
| 0.03% | VOR | VOR BIOPHARMA INC | -- | $24,345.34 | 1,693 | BRJJYT3 |
| 0.03% | CRMD | CORMEDIX INC | -- | $24,269.42 | 3,206 | BJ0LT31 |
| 0.03% | SLDB | SOLID BIOSCIENCES INC | -- | $23,646.30 | 3,174 | BQHN6C7 |
| 0.03% | PSNL | PERSONALIS INC | -- | $23,424.50 | 4,259 | BJQ0608 |
| 0.03% | ZVRA | ZEVRA THERAPEUTICS INC | -- | $22,671.00 | 2,290 | BLFBZ32 |
| 0.03% | RIGL | RIGEL PHARMACEUTICALS INC | -- | $22,644.96 | 741 | BQD3J33 |
| 0.03% | TRAX | FIRST TRACKS BIOTHERAPEUTICS | -- | $22,636.45 | 1,129 | BS2CR64 |
| 0.03% | MRVI | MARAVAI LIFESCIENCES HLDGS-A | -- | $21,210.48 | 5,958 | BMCWKZ2 |
| 0.03% | UPB | UPSTREAM BIO INC | -- | $20,912.49 | 2,199 | BRCFFK6 |
| 0.03% | TECX | TECTONIC THERAPEUTIC INC | -- | $20,808.00 | 765 | BPBPCG8 |
| 0.03% | ACRS | ACLARIS THERAPEUTICS INC | -- | $20,707.54 | 4,907 | BYV2W40 |
| 0.03% | AQST | AQUESTIVE THERAPEUTICS INC | -- | $20,302.76 | 4,964 | BYVQJ96 |
| 0.03% | KYTX | KYVERNA THERAPEUTICS INC | -- | $20,227.50 | 2,325 | BSMLR16 |
| 0.03% | FULC | FULCRUM THERAPEUTICS INC | -- | $20,162.40 | 2,710 | BJDX8Z9 |
| 0.03% | TRDA | ENTRADA THERAPEUTICS INC | -- | $20,108.40 | 1,560 | BP81RK8 |
| 0.03% | ALLO | ALLOGENE THERAPEUTICS INC | -- | $20,034.12 | 9,148 | BFZNYB7 |
| 0.03% | FDMT | 4D MOLECULAR THERAPEUTICS IN | -- | $19,546.50 | 2,075 | BKLXFX5 |
| 0.03% | LRMR | LARIMAR THERAPEUTICS INC | -- | $19,443.60 | 4,419 | BMXNGZ6 |
| 0.03% | PACB | PACIFIC BIOSCIENCES OF CALIF | -- | $19,421.36 | 12,292 | B4N8MH9 |
| 0.03% | KMDA | KAMADA LTD | -- | $19,136.20 | 2,348 | B2Q9833 |
| 0.02% | LYEL | LYELL IMMUNOPHARMA INC | -- | $18,588.85 | 865 | BTNMG41 |
| 0.02% | ESPR | ESPERION THERAPEUTICS INC | -- | $18,582.39 | 9,729 | BBNBTD2 |
| 0.02% | CADL | CANDEL THERAPEUTICS INC | -- | $18,451.20 | 2,976 | BP0TQC5 |
| 0.02% | AURA | AURA BIOSCIENCES INC | -- | $17,984.64 | 2,584 | BP81R42 |
| 0.02% | RGNX | REGENXBIO INC | -- | $17,910.09 | 2,061 | BZ0G875 |
| 0.02% | AVIR | ATEA PHARMACEUTICALS INC | -- | $17,733.24 | 3,178 | BLN9Z50 |
| 0.02% | NGNE | NEUROGENE INC | -- | $17,266.05 | 629 | BS2F741 |
| 0.02% | LXEO | LEXEO THERAPEUTICS INC | -- | $17,261.51 | 2,971 | BQ6C357 |
| 0.02% | GLPG | GALAPAGOS NV-SPON ADR | -- | $17,165.68 | 604 | B292NQ7 |
| 0.02% | VNDA | VANDA PHARMACEUTICALS INC | -- | $16,532.28 | 2,417 | B12W3P6 |
| 0.02% | ENTA | ENANTA PHARMACEUTICALS INC | -- | $16,205.22 | 1,182 | B9L5200 |
| 0.02% | PBYI | PUMA BIOTECHNOLOGY INC | -- | $15,600.26 | 2,069 | B7F2TY6 |
| 0.02% | IVVD | INVIVYD INC | -- | $15,563.64 | 11,278 | BM8NHS1 |
| 0.02% | CTNM | CONTINEUM THERAPEUTICS INC-A | -- | $15,537.06 | 1,239 | BPRBTY7 |
| 0.02% | NMRA | NEUMORA THERAPEUTICS INC | -- | $15,306.75 | 6,803 | BN4JN37 |
| 0.02% | RCKT | ROCKET PHARMACEUTICALS INC | -- | $15,160.60 | 4,420 | BDFKQ07 |
| 0.02% | SLN | SILENCE THERAPEUTICS PLC-ADR | -- | $14,714.70 | 1,911 | BL5B6Z1 |
| 0.02% | KROS | KEROS THERAPEUTICS INC | -- | $14,098.80 | 1,240 | BM7V485 |
| 0.02% | ALT | ALTIMMUNE INC | -- | $13,963.04 | 5,096 | BFY7DC4 |
| 0.02% | EOLS | EVOLUS INC | -- | $13,902.26 | 2,638 | BDRJH21 |
| 0.02% | IMRX | IMMUNEERING CORP - CLASS A | -- | $13,645.07 | 2,609 | BMVBZF5 |
| 0.02% | SIGA | SIGA TECHNOLOGIES INC | -- | $13,384.44 | 2,916 | 2107437 |
| 0.02% | AVXL | ANAVEX LIFE SCIENCES CORP | -- | $12,718.38 | 3,774 | BYTYP72 |
| 0.02% | ACIU | AC IMMUNE SA | -- | $12,413.91 | 4,097 | BZC0D70 |
| 0.02% | FHTX | FOGHORN THERAPEUTICS INC | -- | $12,320.11 | 2,383 | BMF7DT9 |
| 0.02% | EDIT | EDITAS MEDICINE INC | -- | $12,160.44 | 3,974 | BZ8FPH3 |
| 0.02% | AUTL | AUTOLUS THERAPEUTICS PLC | -- | $12,085.68 | 8,166 | BFMLGR4 |
| 0.02% | LENZ | LENZ THERAPEUTICS INC | -- | $11,826.17 | 1,273 | BQV0J03 |
| 0.01% | CABA | CABALETTA BIO INC | -- | $11,199.76 | 3,916 | BK5MWR1 |
| 0.01% | SGMT | SAGIMET BIOSCIENCES INC-A | -- | $11,051.25 | 1,263 | BP2NYN2 |
| 0.01% | CCCC | C4 THERAPEUTICS INC | -- | $10,923.00 | 3,972 | BKX9NQ0 |
| 0.01% | NBP | NOVABRIDGE BIOSCIENCES | -- | $10,919.91 | 4,569 | BKRRKY7 |
| 0.01% | CHRS | COHERUS ONCOLOGY INC | -- | $10,768.68 | 6,084 | BRK0149 |
| 0.01% | CDXS | CODEXIS INC | -- | $10,366.32 | 3,676 | B5LL2C2 |
| 0.01% | ARCT | ARCTURUS THERAPEUTICS HOLDIN | -- | $10,262.59 | 1,157 | BKC9SX3 |
| 0.01% | VYGR | VOYAGER THERAPEUTICS INC | -- | $9,048.00 | 2,400 | BY7RB53 |
| 0.01% | OBIO | ORCHESTRA BIOMED HOLDINGS IN | -- | $8,962.20 | 2,298 | BPRB2N7 |
| 0.01% | BCYC | BICYCLE THERAPEUTICS PLC-ADR | -- | $8,835.96 | 1,884 | BKDQKM6 |
| 0.01% | REPL | REPLIMUNE GROUP INC | -- | $8,640.34 | 3,362 | BDDVW37 |
| 0.01% | OABI | OMNIAB INC | -- | $8,201.20 | 5,858 | BN13S71 |
| 0.01% | CRBU | CARIBOU BIOSCIENCES INC | -- | $7,910.24 | 3,803 | BNYJR68 |
| 0.01% | LFCR | LIFECORE BIOMEDICAL INC | -- | $7,797.76 | 1,523 | 2517058 |
| 0.01% | QSI | QUANTUM-SI INC | -- | $7,254.05 | 7,954 | BNR5QT9 |
| 0.01% | TKNO | ALPHA TEKNOVA INC | -- | $7,125.33 | 2,179 | BP7L561 |
| 0.01% | HUMA | HUMACYTE INC | -- | $6,658.81 | 7,857 | BMYTJP4 |
| 0.01% | MENS | JYONG BIOTECH LTD | -- | $6,553.40 | 3,020 | BPTK6Z2 |
| 0.01% | BDTX | BLACK DIAMOND THERAPEUTICS I | -- | $6,258.60 | 2,318 | BKTV702 |
| 0.01% | TNYA | TENAYA THERAPEUTICS INC | -- | $6,096.69 | 8,823 | BNNXX52 |
| 0.01% | AARD | AARDVARK THERAPEUTICS INC | -- | $4,952.74 | 886 | BTXQTX3 |
| 0.01% | PEPG | PEPGEN INC | -- | $4,424.00 | 2,800 | BMTX3D7 |
| 0.01% | PYXS | PYXIS ONCOLOGY INC | -- | $4,309.50 | 2,535 | BLBR8D5 |
| -- | RANI | RANI THERAPEUTICS HOLDINGS-A | -- | $3,446.83 | 3,971 | BNNXX18 |
| -- | GOSS | GOSSAMER BIO INC | -- | $3,248.61 | 9,419 | BJ0CK86 |
| -- | 2324462D | CARTESIAN THERAPEUTICS-CVR | -- | $00.00 | 9,785 | BM9HFX3 |
| -- | THRD | THIRD HARMONIC BIO INC | -- | $00.00 | 1,662 | BNNPQY8 |
| 34.30% | -- | NASDAQ BIO INDEX SWAP BNP PARIBAS | 25,728,633 | -- | 4,415 | -- |
| 28.76% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP BANK OF AMERICA NA | 21,573,590 | -- | 3,702 | -- |
| 27.38% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP CITIBANK NA | 20,536,286 | -- | 3,524 | -- |
| 20.50% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP GOLDMAN SACHS INTERNATIONAL | 15,378,904 | -- | 2,639 | -- |
| 17.10% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP SOCIETE GENERALE | 12,826,438 | -- | 2,201 | -- |
| 4.92% | -- | NASDAQ BIOTECHNOLOGY INDEX SWAP UBS AG | 3,688,839 | -- | 633 | -- |
| -- | -- | NET OTHER ASSETS (LIABILITIES) | -- | $24,845,751.02 | 24,845,751 | -- |
Index
as of 3/31/2026
- Total Number of Companies256
- Price/Book Ratio3.78
- Dividend Yield ( % )0.85
- Avg. Index Market Capitalization$6.50 billion
About the Index
The Nasdaq Biotechnology Index is designed to measure the performance of a set of Nasdaq-listed biotechnology and pharmaceutical companies.
Distributions
For
2026
- 2026
- 2025
- 2024
- 2023
- 2022
| Ex-Dividend Date | Record Date | Payable Date | Dividend | Long-Term Capital Gain | Short-Term Capital Gain | Return of Capital |
|---|
Portfolio Hedging Series
Part I: The Significance of Portfolio Hedging
Investing involves risk. Market downturns will happen. Having a sound investment strategy can help smooth out the turbulence in your portfolio and save you from getting caught up in a herd mentality of selling low into a down market.
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